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Número de aplicación: 6,723,323 Fecha de publicación: 20-04-2004 Vibrio Cholerae vaccine candidates and method of their constructing (72 Kb) Resumen Vibrio cholerae vaccine strains which have a disrupted hap gene and which are tagged with celA coding functions from Clostridium thermocellum are described. A contained, genetically defined thyA mutant of Vibrio cholerae and the general methodology of making along with the sequence of thyA gene are also described. |


