Número de aplicación: 6,723,323
Fecha de publicación: 20-04-2004
Vibrio Cholerae vaccine candidates and method of their constructing (72 Kb)
Vibrio cholerae vaccine strains which have a disrupted hap gene and which are tagged with celA coding functions from Clostridium thermocellum are described. A contained, genetically defined thyA mutant of Vibrio cholerae and the general methodology of making along with the sequence of thyA gene are also described.
Javier Campos, Rafael Fando, Tec. Boris Ernesto Ruiz Janeiro, Edgar Valle, Talena Ledón, Dr. Jorge A. Benitez